Link: https://my.clevelandclinic.org/health/diseases/15612-mitochondrial-diseases
Description: WebYes. Mitochondrial dysfunction occurs when mitochondria don’t work as well as they should due to another disease or condition. Many conditions can lead to secondary mitochondrial dysfunction, including: Alzheimer’s disease. Muscular dystrophy. Type 1 diabetes. Multiple sclerosis (MS). Cancer.
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Link: https://www.ninds.nih.gov/health-information/disorders/mitochondrial-disorders
Description: WebFeb 28, 2024 · Mitochondrial disorders are caused by defects in mitochondria, which are energy factories found inside almost all the cells in the body. There are many types of mitochondrial disorders. They can affect one part of the body or many parts, including the brain, muscles, kidneys, heart, eyes, and ears.
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Link: https://www.medicalnewstoday.com/articles/mitochondrial-disease
Description: WebSep 12, 2023 · Types. Symptoms. Causes and risk factors. Complications. Diagnosis. Treatment. Outlook. Summary. Mitochondrial disease refers to a group of conditions that affect how mitochondria work. While...
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Link: https://en.wikipedia.org/wiki/Mitochondrial_disease
Description: WebMitochondrial disorders may be caused by mutations (acquired or inherited), in mitochondrial DNA (mtDNA), or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondrial dysfunction due to adverse effects of drugs, infections, or other environmental causes.
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Link: https://www.nature.com/articles/s41598-023-34624-8
Description: WebMay 17, 2023 · Evidence suggests that mitochondrial dysfunction may often precede other pathological signs in these disorders, further modulated by genetics, environment, and lifestyle. This Collection aimed...
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Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785072/
Description: WebNov 30, 2022 · Mitochondrial dysfunction is a potential target for diagnostic and therapeutic interventions for many diseases owing to its role concerning higher cell death, decreased ATP synthesis, and increased mtROS production in …
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Link: https://www.healthline.com/health/mitochondrial-disease
Description: WebSep 29, 2022 · Symptoms. Causes. Diagnosis. Prevention. Risk factors. Outlook. FAQs. Bottom line. Mitochondria are structures that are found within the cells of your body. Their main function is to use oxygen,...
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Link: https://www.mayoclinic.org/departments-centers/clinical-genomics/overview/specialty-groups/mitochondrial-disease-clinic
Description: WebMitochondrial disease results from failure of mitochondria to function properly. This can lead to less energy, cell injury and cell death. The most common organs that may experience damage are the brain, heart, liver, muscles, kidneys and the endocrine system.
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Link: https://medlineplus.gov/mitochondrialdiseases.html
Description: WebAug 23, 2016 · When the mitochondria are defective, the cells do not have enough energy. The unused oxygen and fuel molecules build up in the cells and cause damage. The symptoms of mitochondrial disease can vary. It depends on how many mitochondria are defective, and where they are in the body.
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Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208355/
Description: WebPrimary mitochondrial disease encompasses an impressive range of inherited energy deficiency disorders having highly variable molecular etiologies as well as clinical onset, severity, progression, and response to therapies of multi-system manifestations.
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