Link: https://www.ncbi.nlm.nih.gov/books/NBK537083/
Description: WEBAug 14, 2023 · Mechanism of Action. As a first-generation antipsychotic, prochlorperazine mainly blocks D2 dopamine receptors in the brain. It can also block histaminergic, cholinergic, and noradrenergic receptors. One study found that prochlorperazine also inhibits the P2X7 receptor in human macrophages but not in …
DA: 82 PA: 86 MOZ Rank: 2
Link: https://go.drugbank.com/drugs/DB00433
Description: WEBThe mechanism of action of prochlorperazine has not been fully determined, but may be primarily related to its anti-dopaminergic effects. Prochlorperazine blocks the D2 dopamine receptors in the brain, which are somatodendritic autoreceptors.
DA: 1 PA: 58 MOZ Rank: 91
Link: https://www.medicine.com/drug/prochlorperazine/hcp
Description: WEBFeb 17, 2020 · Mechanism of Action. Prochlorperazine is a piperazine phenothiazine antipsychotic which blocks postsynaptic mesolimbic dopaminergic D 1 and D 2 receptors in the brain, including the chemoreceptor trigger zone; exhibits a strong alpha-adrenergic and anticholinergic blocking effect and depresses the release of …
DA: 45 PA: 28 MOZ Rank: 83
Link: https://en.wikipedia.org/wiki/Prochlorperazine
Description: WEBProchlorperazine, formerly sold under the brand name Compazine among others, is a medication used to treat nausea, migraines, schizophrenia, psychosis and anxiety. It is a less preferred medication for anxiety. It may be taken by mouth, rectally, injection into a vein, or injection into a muscle.
DA: 32 PA: 19 MOZ Rank: 71
Link: https://www.aafp.org/pubs/afp/issues/2004/0301/p1169.html
Description: WEBMar 1, 2004 · Intravenous metoclopramide (Reglan) and intravenous, intramuscular, or rectal prochlorperazine (Compazine) are recommended for treatment of patients with nausea and acute migraine.
DA: 71 PA: 86 MOZ Rank: 84
Link: https://pubmed.ncbi.nlm.nih.gov/30725768/
Description: WEBThis activity outlines the indications, mechanism of action, methods of administration, significant adverse effects, contraindications, monitoring, and toxicity of prochlorperazine, so providers can direct patient therapy in treating conditions for which it is indicated as part of the interprofessional team.
DA: 8 PA: 9 MOZ Rank: 89
Link: https://www.drugs.com/pro/compazine.html
Description: WEBMar 25, 2024 · Compazine. FDA PI. Print. Save. Compazine Prescribing Information. Package insert / product label. Generic name: prochlorperazine maleate. Dosage form: tablet, film coated. Drug classes: Phenothiazine antiemetics, Phenothiazine antipsychotics. Medically reviewed by Drugs.com. Last updated on Mar 25, 2024.
DA: 57 PA: 96 MOZ Rank: 28
Link: https://go.drugbank.com/drugs/DBSALT003068
Description: WEBProchlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.
DA: 84 PA: 100 MOZ Rank: 40
Link: https://www.mayoclinic.org/drugs-supplements/prochlorperazine-oral-route/description/drg-20406263
Description: WEBCompazine; Descriptions. Prochlorperazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety. It is also used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.
DA: 3 PA: 61 MOZ Rank: 77
Link: https://www.statpearls.com/point-of-care/27768
Description: WEBAug 14, 2023 · Already have an account? Log in. Point of Care - Clinical decision support for Prochlorperazine. Treatment and management. Indications, Mechanism of Action, Administration, Adverse Effects, Contraindications, Monitoring, Toxicity, Enhancing Healthcare Team Outcomes.
DA: 51 PA: 13 MOZ Rank: 80
